Your role
As the statistician on the team, your job is to help your team make informed decisions on study design considerations, including:
- Decide on the number of clusters (health facilities) to include.
- Buffer for drop-out.
- Determining the necessary sample size and power for primary and secondary endpoints.
- Adjust for ICC.
Available data
In order to help you perform these critical calculations, we have pre-loaded all the fact sheets and data that your various team members have access to.
This includes:
epi
: data on malaria prevalence, incidence and test positivity ratehealth_facilities
: data on health facilities in each region, the population they serve, and expected malaria cases per month
cost_per_hf
: fixed cost per health facility enrolled (in USD), including training, equipment, and administrative expenses.cost_per_sample
: cost per sample enrolled (in USD), including collection, laboratory testing, consumables, and data managementcost_transport_coast
: transport cost per health facility (in USD) in the Coastal regioncost_transport_highland
: transport cost per health facility (in USD) in the Highland regioncost_transport_forest
: transport cost per health facility (in USD) in the Forest regioncost_transport_urban
: transport cost per health facility (in USD) in the Urban region
We have also pre-loaded the DRpower R package so you can access its functions if you need to!
Exercise
You can use the below R code box to perform your calculations